Time from dementia diagnosis to nursing-home admission and death among persons with dementia: A multistate survival analysis
Mjørud, Marit; Selbæk, Geir; Bjertness, Espen; Edwin, Trine Holt; Engedal, Knut; Knapskog, Anne Brita; Strand, Bjørn Heine
Peer reviewed, Journal article
Published version
Permanent lenke
https://hdl.handle.net/11250/3062617Utgivelsesdato
2020Metadata
Vis full innførselSamlinger
Sammendrag
Objectives: To estimate transition times from dementia diagnosis to nursing-home (NH) admission or death and to examine whether sex, education, marital status, level of cognitive impairment and dementia aetiology are associated with transition times. Design: Markov multistate survival analysis and flexible parametric models. Setting: Participants were recruited from the Norwegian Registry of Persons Assessed for Cognitive Symptoms (NorCog) in specialist healthcare between 2008 and 2017 and followed until August 2019, a maximum of 10.6 years follow-up time (mean 4.4 years, SD 2.2). Participants’ address histories, emigration and vital status were retrieved from the National Population Registry from time of diagnosis and linked to NorCog clinical data. Participants 2,938 home-dwelling persons with dementia, ages 40–97 years at time of diagnosis (mean 76.1, SD 8.5). Results: During follow-up, 992 persons (34%) were admitted to nursing-homes (NHs) and 1,556 (53%) died. Approximately four years after diagnosis, the probability of living in a NH peaked at 19%; thereafter, the probability decreased due to mortality. Median elapsed time from dementia diagnosis to NH admission among those admitted to NHs was 2.28 years (IQR 2.32). The probability of NH admission was greater for women than men due to women´s lower mortality rate. Persons living alone, particularly men, had a higher probability of NH admission than cohabitants. Age, dementia aetiology and severity of cognitive impairment at time of diagnosis did not influence the probability of NH admission. Those with fewer than 10 years of education had a lower probability of NH admission than those with 10 years or more, and this was independent of the excess mortality in the less-educated group. Conclusion: Four years after diagnosis, half of the participants still lived at home, while NH residency peaked at 19%. Those with fewer than 10 years of education were less often admitted to NH.
Utgiver
SageTidsskrift
PLOS ONEOpphavsrett
© 2020 Mjørud et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Beslektede innførsler
Viser innførsler beslektet ved tittel, forfatter og emneord.
-
Temporal changes in cardiorespiratory fitness and risk of dementia incidence and mortality: a population-based prospective cohort study
Tari, Atefe R; Nauman, Javaid; Zisko, Nina; Skjellegrind, Håvard; Bosnes, Ingunn; Bergh, Sverre; Stensvold, Dorthe; Selbæk, Geir; Wisløff, Ulrik (Peer reviewed; Journal article, 2019)Cardiorespiratory fitness is associated with risk of dementia, but whether temporal changes in cardiorespiratory fitness influence the risk of dementia incidence and mortality is still unknown. We aimed to study whether ... -
The course of neuropsychiatric symptoms in nursing home residents from admission to 30-month follow-up
Helvik, Anne-Sofie; Selbæk, Geir; Saltyte Benth, Jurate; Røen, Irene Mari; Bergh, Sverre (Peer reviewed; Journal article, 2018)Aim The aim of this study was to describe the prevalence and persistence of clinically significant neuropsychiatric symptoms (NPS) in nursing home residents with dementia, and to study the association between severity ... -
TIME – Targeted interdisciplinary model for evaluation and treatment of neuropsychiatric symptoms : protocol for an effectiveness-implementation cluster randomized hybrid trial
Lichtwarck, Bjørn; Selbæk, Geir; Kirkevold, Øyvind; Rokstad, Anne Marie Mork; Saltyte Benth, Jurate; Myhre, Janne; Nybakken, Solvor; Bergh, Sverre (Journal article; Peer reviewed, 2016)Background: Nearly all persons with dementia will experience neuropsychiatric symptoms (NPS) during the course of their disease. Clinicians and researchers emphasize the need for an evidence-informed standardized approach ...