Show simple item record

dc.contributor.authorFurlong, Eileen
dc.contributor.authorDarley, Andrew
dc.contributor.authorFox, Patricia A.
dc.contributor.authorBuick, Alison R.
dc.contributor.authorKotronoulas, Grigorios
dc.contributor.authorMiller, Morven
dc.contributor.authorFlowerday, Adrian
dc.contributor.authorMiaskowski, Christine
dc.contributor.authorPatiraki, Elisabeth
dc.contributor.authorKatsaragakis, Stylianos
dc.contributor.authorReam, Emma
dc.contributor.authorArmes, Jo
dc.contributor.authorGaiger, Alexander
dc.contributor.authorBerg, Geir Vegard
dc.contributor.authorMcCrone, Paul
dc.contributor.authorDonnan, Peter
dc.contributor.authorMcCann, Lisa
dc.contributor.authorMaguire, Roma
dc.identifier.citationJMIR Cancer. 2019, 5(1):e10813, 1-14. doi: 10.2196/10813.nb_NO
dc.description.abstractBACKGROUND: There has been an international shift in health care, which has seen an increasing focus and development of technological and personalized at-home interventions that aim to improve health outcomes and patient-clinician communication. However, there is a notable lack of empirical evidence describing the preparatory steps of adapting and implementing technology of this kind across multiple countries and clinical settings. OBJECTIVE: This study aimed to describe the steps undertaken in the preparation of a multinational, multicenter randomized controlled trial (RCT) to test a mobile phone-based remote symptom monitoring system, that is, Advanced Symptom Management System (ASyMS), designed to enhance management of chemotherapy toxicities among people with cancer receiving adjuvant chemotherapy versus standard cancer center care. METHODS: There were 13 cancer centers across 5 European countries (Austria, Greece, Ireland, Norway, and the United Kingdom). Multiple steps were undertaken, including a scoping review of empirical literature and clinical guidelines, translation and linguistic validation of study materials, development of standardized international care procedures, and the integration and evaluation of the technology within each cancer center. RESULTS: The ASyMS was successfully implemented and deployed in clinical practices across 5 European countries. The rigorous and simultaneous steps undertaken by the research team highlighted the strengths of the system in clinical practice, as well as the clinical and technical changes required to meet the diverse needs of its intended users within each country, before the commencement of the RCT. CONCLUSIONS: Adapting and implementing this multinational, multicenter system required close attention to diverse considerations and unique challenges primarily related to communication and clinical and technical issues. Success was dependent on collaborative and transparent communication among academics, the technology industry, translation partners, patients, and clinicians as well as a simultaneous and rigorous methodological approach within the 5 relevant countries.nb_NO
dc.description.sponsorshipThis project received funding from the European Union’s Seventh Framework Programme for research, technological development, and demonstration under grant agreement number 602289.nb_NO
dc.publisherJMIR Cancernb_NO
dc.rightsNavngivelse 4.0 Internasjonal*
dc.subjectcancer; methods; patient care; symptom management; telemedicinenb_NO
dc.titleAdaptation and implementation of a mobile phone-based remote symptom monitoring system for people with cancer in Europenb_NO
dc.typePeer reviewednb_NO
dc.typeJournal articlenb_NO
dc.rights.holder©Eileen Furlong, Andrew Darley, Patricia Fox, Alison Buick, Grigorios Kotronoulas, Morven Miller, Adrian Flowerday, Christine Miaskowski, Elisabeth Patiraki, Stylianos Katsaragakis, Emma Ream, Jo Armes, Alexander Gaiger, Geir Berg, Paul McCrone, Peter Donnan, Lisa McCann, Roma Maguire. Originally published in JMIR Cancer (, 14.03.2019. This is an open-access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Cancer, is properly cited. The complete bibliographic information, a link to the original publication on, as well as this copyright and license information must be included.nb_NO
dc.source.journalJMIR Cancernb_NO
cristin.unitnameDiv Lillehammer

Files in this item


This item appears in the following Collection(s)

Show simple item record

Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal