Blar i Artikler på forfatter "Engedal, Knut"
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A 52 month follow-up of functional decline in nursing home residents - Degree of dementia contributes
Helvik, Anne-Sofie; Engedal, Knut; Saltyte Benth, Jurate; Selbæk, Geir (Peer reviewed; Journal article, 2014)Background: Few have studied how personal activities of daily living (P-ADL) develop over time in nursing home residents with dementia. Thus, the aim was to study variables associated with the development of P-ADL functioning ... -
Distinguishing early and late brain aging from the Alzheimer's disease spectrum: Consistent morphological patterns across independent samples
Doan, Nhat Trung; Engvig, Andreas; Zaske, Krystal; Persson, Karin; Lund, Martina Jonette; Kaufmann, Tobias; Còrdova Palomera, Aldo; Alnæs, Dag; Moberget, Torgeir; Brækhus, Anne; Barca, Maria Lage; Nordvik, Jan Egil; Engedal, Knut; Agartz, Ingrid; Selbæk, Geir; Andreassen, Ole Andreas; Westlye, Lars Tjelta (Journal article; Peer reviewed, 2017)Abstract Alzheimer's disease (AD) is a debilitating age-related neurodegenerative disorder. Accurate identification of individuals at risk is complicated as AD shares cognitive and brain features with aging. We applied ... -
MRI-based classification models in prediction of mild cognitive impairment and dementia in late-life depression
Lebedeva, Aleksandra K.; Westman, Eric; Borza, Tom; Beyer, Mona K.; Engedal, Knut; Aarsland, Dag; Selbæk, Geir; Håberg, Asta (Journal article; Peer reviewed, 2017)Objective: Late-life depression (LLD) is associated with development of different types of dementia. Identification of LLD patients, who will develop cognitive decline, i.e., the early stage of dementia would help to ... -
Persistent use of psychotropic drugs in nursing home residents in Norway
Helvik, Anne-Sofie; Saltyte Benth, Jurate; Wu, Bei; Engedal, Knut; Selbæk, Geir (Journal article; Peer reviewed, 2017)Background The prevalence of psychotropic drug (PTD) use in NH residents is high, but few have explored prevalence and persistency in PTD in NH residents and factors associated with persistency. This at the same time as ... -
The Relationships among Tryptophan, Kynurenine, Indoleamine 2,3-Dioxygenase, Depression, and Neuropsychological Performance
Hestad, Knut; Engedal, Knut; Whist, Jon Elling; Farup, Per Grønaas (Journal article; Peer reviewed, 2017)It has been suggested that the metabolic enzyme indoleamine 2,3-dioxygenase (IDO) is a biological mediator of inflammation related to the psychopathology of depression, with a Kynurenine (KYN) increase in the Tryptophan ... -
Time from Symptom Debut to Dementia Assessment by the Specialist Healthcare Service in Norway
Helvik, Anne-Sofie; Engedal, Knut; Saltyte Benth, Jurate; Selbæk, Geir (Journal article; Peer reviewed, 2018)Objectives: We described the duration from symptom debut to assessment at specialist healthcare outpatient clinics for dementia in Norway and explored whether educational level was associated with time from symptom debut ...