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    • A 52 month follow-up of functional decline in nursing home residents - Degree of dementia contributes 

      Helvik, Anne-Sofie; Engedal, Knut; Saltyte Benth, Jurate; Selbæk, Geir (Journal article; Peer reviewed, 2014)
      Background: Few have studied how personal activities of daily living (P-ADL) develop over time in nursing home residents with dementia. Thus, the aim was to study variables associated with the development of P-ADL functioning ...
    • A systematic review of trials evaluating success factors of interventions with computerised clinical decision support 

      van de Velde, Stijn Rita Patrick; Heselmans, Annemie; Delvaux, Nicolas; Brandt, Linn; Marco-Ruiz, Luis; Spitaels, David; Cloetens, Hanne; Kortteisto, Tiina; Roshanov, Pavel; Kunnamo, Ilkka; Aertgeerts, Bert; Vandvik, Per Olav; Flottorp, Signe Agnes (Journal article; Peer reviewed, 2018)
      BACKGROUND: Computerised clinical decision support (CDS) can potentially better inform decisions, and it can help with the management of information overload. It is perceived to be a key component of a learning health ...
    • A tailored intervention to implement guideline recommendations for elderly patients with depression in primary care: A pragmatic cluster randomised trial 

      Aakhus, Eivind; Granlund, Ingeborg; Odegaard-Jensen, Jan; Oxman, Andrew David; Flottorp, Signe (Journal article; Peer reviewed, 2016)
      Background Elderly patients with depression are underdiagnosed, undertreated and run a high risk of a chronic course. General practitioners adhere to clinical practice guidelines to a limited degree. In the international ...
    • Acute effects of post-absorptive and postprandial moderate exercise on markers of inflammation in hyperglycemic individuals 

      Nygård, Håvard; Slettaløkken, Gunnar; Whist, Jon Elling; Hollan, Ivana; Ellefsen, Stian; Holmboe-Ottesen, Gerd; Rønnestad, Bent; Høstmark, Arne Torbjørn (Journal article; Peer reviewed, 2017)
      Abstract Purpose Systemic inflammation is involved in the development of several diseases, including cardiovascular disease and type 2 diabetes. It is known that vigorous exercise affects systemic inflammation, but less ...
    • Altered neuroendocrine control and association to clinical symptoms in adolescent chronic fatigue syndrome: a cross-sectional study 

      Wyller, Vegard Bruun; Vitelli, Valeria; Sulheim, Dag; Fagermoen, Frode Even; Winger, Anette; Godang, Kristin; Bollerslev, Jens (Journal article; Peer reviewed, 2016)
      Background Chronic fatigue syndrome (CFS) is a common and disabling disorder, and a major threat against adolescent health. The pathophysiology is unknown, but alteration of neuroendocrine control systems might be a ...
    • Ambiguous participation in older hospitalized patients: gaining influence through active and passive approaches - a qualitative study 

      Nyborg, Ingrid; Kvigne, Kari; Danbolt, Lars Johan; Kirkevold, Marit (Journal article; Peer reviewed, 2016)
      Background: Patient participation is required by law in Norway and in several western countries. Current participation ideology is based on individualism, which may conflict with the older generation’s commonly held values ...
    • Anti-rheumatic treatment is not associated with reduction of pentraxin 3 in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis 

      Deyab, Gia; Hokstad, Ingrid; Whist, Jon Elling; Småstuen, Milada Cvancarova; Agewall, Stefan; Lyberg, Torstein; Bottazzi, Barbara; Meroni, Pier Luigi; Leone, Roberto; Hjeltnes, Gunnbjørg; Hollan, Ivana (Journal article; Peer reviewed, 2017)
      Background Pentraxin 3 is proposed to be a marker of inflammation and cardiovascular risk, but its role in inflammatory rheumatic diseases (IRDs) is still uncertain. Therefore, we wanted to examine if anti-rheumatic ...
    • Arti Hurria and the progress in integrating the geriatric assessment into oncology: Young international society of geriatric oncology review paper 

      DuMontier, Clark; Sedrak, Mina S.; Soo, Wee Kheng; Kenis, Cindy; Williams, Grant R.; Haase, Kristen; Harneshaug, Magnus; Mian, Hira; Loh, Kah Poh; Rostoft, Siri; Dale, William; Cohen, Harvey Jay (Journal article; Peer reviewed, 2019)
      Abstract Until recently, the progress in the diagnosis and management of cancer has not been matched by similar progress in the assessment of the increasing numbers of older and more complex patients with cancer. Dr. ...
    • Assessment of dietary intake of fluoride and maximum limits of fluoride in food supplements 

      Løvik, Martinus; Dahl, Lisbeth; Mangschou, Bente; Ulven, Stine Marie; Andersen, Lene Frost; Dalen, Knut Tomas; Holvik, Kristin; Parr, Christine Louise; Stea, Tonje Holte; Strand, Tor A (VKM Report;, Research report, 2019)
      Abstract The Norwegian Scientific Committee for Food and Environment (Vitenskapskomiteen for mat og miljø, VKM) has, at the request of the Norwegian Food Safety Authority (Mattilsynet, NFSA), evaluated the intake of ...
    • Attachment styles of dermatological patients in europe: A multicentre study in 13 countries 

      Szabo, Csanad; Altmayer, Anita; Lien, Lars; Poot, Francoise; Gieler, Uwe; Tómas-Aragonés, Lucía; Kupfer, Jörg; Jemec, Gregor B E; Misery, Laurent; Linder, Dennis; Sampogna, Francesca; Van Middendorp, Henriet; Halvorsen, Jon Anders; Balieva, Flora Nicol; Szepietowski, Jacek C.; Romanov, Dmitry; Marrón, Servando E.; Altunay, Ilknur K; Finlay, Andrew Y.; Salek, Sam S; Dalgard, Florence (Journal article; Peer reviewed, 2017)
      Attachment styles of dermatological outpatients and satisfaction with their dermatologists were investigated within the framework of a multicentre study conducted in 13 European countries, organized by the European Society ...
    • Changes in C-reactive protein, neopterin and lactoferrin differ after conservative and surgical weight loss in individuals with morbid obesity 

      Aasbrenn, Martin; Farup, Per Grønaas; Videm, Vibeke (Journal article; Peer reviewed, 2019)
      Abstract C-reactive protein, neopterin and lactoferrin are biomarkers of atherosclerotic disease. We aimed to assess changes in these biomarkers after conservative and surgical weight loss interventions in individuals ...
    • Cognitive Functions and Depression in Patients with Irritable Bowel Syndrome 

      Farup, Per Grønaas; Hestad, Knut (Journal article; Peer reviewed, 2015)
      Background. Irritable bowel syndrome (IBS) is associated with depression and depression with impaired cognitive functions. The primary aim was to study associations between depression and cognitive functions in patients ...
    • Comparative effectiveness of loop diuretics on mortality in the treatment of patients with chronic heart failure – A multicenter propensity score matched analysis 

      Täger, Tobias; Fröhlich, Hanna; Grundtvig, Morten; Seiz, Mirjam; Schellberg, Dieter; Goode, Kevin; Kazmi, Syed; Hole, Torstein; Katus, Hugo A.; Atar, Dan; Cleland, John G.F.; Agewall, Stefan; Clark, Andrew L.; Frankenstein, Lutz (Journal article; Peer reviewed, 2019)
      Abstract BACKGROUND: Loop diuretics are given to the majority of patients with chronic heart failure (HF). Whether the different pharmacological properties of the three guideline-recommended loop diuretics result in ...
    • Crystallized but not soluble uric acid elicits pro-inflammatory response in short-term whole blood cultures from healthy men 

      Brovold, Henrik; Lund, Trine; Svistounov, Dmitri; Solbu, Marit Dahl; Jenssen, Trond Geir; Ytrehus, Kirsti; Zykova, Svetlana (Research report, 2019)
      Several epidemiological studies have pointed at serum uric acid (SUA) as an independent risk factor for mortality, diabetes, hypertension, cardiovascular and kidney disease; however, no clear pathogenic pathway is established. ...
    • CSF neurofilament light levels predict hippocampal atrophy in cognitively healthy older adults 

      Idland, Ane-Victoria; Roser, Sala-Llonch; Borza, Tom; Watne, Leiv Otto; Wyller, Torgeir Bruun; Brækhus, Anne; Zetterberg, Henrik; Blennow, Kaj; Walhovd, Kristine B; Fjell, Anders Martin (Journal article; Peer reviewed, 2017)
      Cerebrospinal fluid (CSF) neurofilament light (NFL) is a marker of axonal degeneration. We tested whether CSF NFL levels predict hippocampal atrophy rate in cognitively healthy older adults independently of the established ...
    • Decompression alone versus decompression with instrumental fusion the NORDSTEN degenerative spondylolisthesis trial (NORDSTEN-DS); study protocol for a randomized controlled trial 

      Austevoll, Ivar Magne; Hermansen, Erland; Fagerland, Morten; Rekeland, Frode; Solberg, Tore; Storheim, Kjersti; Brox, Jens Ivar; Lønne, Greger; Indrekvam, Kari; Aaen, Jørn; Grundnes, Oliver; Hellum, Christian (Journal article; Peer reviewed, 2019)
      BACKGROUND: Fusion in addition to decompression has become the standard treatment for lumbar spinal stenosis with degenerative spondylolisthesis (DS). The evidence for performing fusion among these patients is conflicting ...
    • Determinants of adherence to recommendations for depressed elderly patients in primary care: A multi-methods study 

      Aakhus, Eivind; Oxman, Andrew David; Flottorp, Signe Agnes (Peer reviewed; Journal article, 2014)
      Objective: It is logical that tailoring implementation strategies to address identified determinants of adherence to clinical practice guidelines should improve adherence. This study aimed to identify and prioritize ...
    • Diagnosis and Treatment of Genetic HFE-Hemochromatosis: The Danish Aspect 

      Milman, Nils Thorm; Schioedt, Frank Vinholt; Junker, Anders Ellekaer; Magnussen, Karin (Journal article, 2019)
      This paper outlines the Danish aspects of HFE-hemochromatosis, which is the most frequent genetic predisposition to iron overload in the five million ethnic Danes; more than 20,000 people are homozygous for the C282Y ...
    • Dipeptidyl peptidase-4 inhibitors and risk of heart failure in type 2 diabetes: Systematic review and meta-analysis of randomised and observational studies 

      Li, Ling; Li, Sheyu; Deng, Ke; Liu, Jiali; Vandvik, Per Olav; Zhao, Pujing; Zhang, Longhao; Shen, Jiantong; Bala, Malgorzata M.; Sohani, Zahra N.; Wong, Evelyn; Busse, Jason Walter; Ebrahim, Shanil; Malaga, German; Rios, Lorena P.; Wang, Yingqiang; Chen, Qunfei; Guyatt, Gordon Henry; Sun, Xin (Journal article; Peer reviewed, 2016)
      Objectives To examine the association between dipeptidyl peptidase-4 (DPP-4) inhibitors and the risk of heart failure or hospital admission for heart failure in patients with type 2 diabetes. Design Systematic review ...
    • Distinguishing early and late brain aging from the Alzheimer's disease spectrum: Consistent morphological patterns across independent samples 

      Doan, Nhat Trung; Engvig, Andreas; Zaske, Krystal; Persson, Karin; Lund, Martina Jonette; Kaufmann, Tobias; Còrdova Palomera, Aldo; Alnæs, Dag; Moberget, Torgeir; Brækhus, Anne; Barca, Maria Lage; Nordvik, Jan Egil; Engedal, Knut; Agartz, Ingrid; Selbæk, Geir; Andreassen, Ole Andreas; Westlye, Lars Tjelta (Journal article; Peer reviewed, 2017)
      Abstract Alzheimer's disease (AD) is a debilitating age-related neurodegenerative disorder. Accurate identification of individuals at risk is complicated as AD shares cognitive and brain features with aging. We applied ...

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