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dc.contributor.authorHelvik, Anne-Sofie
dc.contributor.authorSaltyte Benth, Jurate
dc.contributor.authorWu, Bei
dc.contributor.authorEngedal, Knut
dc.contributor.authorSelbæk, Geir
dc.identifier.citationBMC Geriatrics. 2017 Feb 13;17(1):52., DOI:
dc.description.abstractBackground The prevalence of psychotropic drug (PTD) use in NH residents is high, but few have explored prevalence and persistency in PTD in NH residents and factors associated with persistency. This at the same time as we know that risk of side events may be higher with long- term use in older adults. Thus, the aim of this study was to describe the prevalence and persistence in use of PTD and to explore factors associated with persistence in use of PTD at two consecutive time points in nursing home (NH) residents. Methods We included 1163 NH residents in a 72-month longitudinal study with five assessments. Use of PTD, neuropsychiatric symptoms (NPS), severity of dementia and physical health were assessed each time. Results The prevalence over time and persistent use of antipsychotic drugs, antidepressants, anxiolytics and sedatives at two consecutive time points were high in residents with and without dementia. There was an association between greater NPS at the first time point, and persistent use of these drugs, but changes in NPS between time points, did not explain such use. A longer NH stay increased the odds for persistent use of antipsychotics. Conclusion Psychotropic drugs are frequently used as a long-term treatment among NH residents and are associated with severity of neuropsychiatric symptoms, but not with severity of dementia. Closer attention should be paid to follow-up of psychotropic drug treatment, and especially for long –term use of antipsychotics, since the duration of such treatment should be as short as possible.nb_NO
dc.description.abstractPersistent use of psychotropic drugs in nursing home residents in Norwaynb_NO
dc.description.sponsorshipData collection was funded by unrestricted grants from the Eastern Norway Regional Health authorities.nb_NO
dc.rightsNavngivelse-Ikkekommersiell-DelPåSammeVilkår 4.0 Internasjonal*
dc.subjectATC, Dementia, Older adults, Geriatrics, Long-term-use, Neuropsychiatric symptoms, Old agenb_NO
dc.titlePersistent use of psychotropic drugs in nursing home residents in Norwaynb_NO
dc.title.alternativePersistent use of psychotropic drugs in nursing home residents in Norwaynb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.rights.holder© The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.nb_NO
dc.source.journalBMC Geriatricsnb_NO
cristin.unitnameAvd Alderspsykiatri

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Navngivelse-Ikkekommersiell-DelPåSammeVilkår 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse-Ikkekommersiell-DelPåSammeVilkår 4.0 Internasjonal