• A systematic review of trials evaluating success factors of interventions with computerised clinical decision support 

      van de Velde, Stijn Rita Patrick; Heselmans, Annemie; Delvaux, Nicolas; Brandt, Linn; Marco-Ruiz, Luis; Spitaels, David; Cloetens, Hanne; Kortteisto, Tiina; Roshanov, Pavel; Kunnamo, Ilkka; Aertgeerts, Bert; Vandvik, Per Olav; Flottorp, Signe Agnes (Journal article; Peer reviewed, 2018)
      BACKGROUND: Computerised clinical decision support (CDS) can potentially better inform decisions, and it can help with the management of information overload. It is perceived to be a key component of a learning health ...
    • Atraumatic (pencil-point) versus conventional needles for lumbar puncture: A clinical practice guideline 

      Rochwerg, B; Almenawer, S. A.; Siemieniuk, Reed Alexander C; Vandvik, Per Olav; Agoritsas, Thomas; Lytvyn, Lyubov; Alhazzani, Waleed; Archambault, Patrick; D'Aragon, Frédérick; Farhoumand, Pauline Darbellay; Guyatt, Gordon Henry; Laake, Jon Henrik; Beltrán-Arroyave, Claudia; McCredie, Victoria; Price, Amy; Chabot, Christian; Zervakis, Tracy; Badhiwala, Jetan; St-Onge, Maude; Szczeklik, Wojciech; Møller, Morten Hylander; Lamontagne, François (Peer reviewed; Journal article, 2018)
      Is the needle tip configuration important when performing a lumbar puncture for any indication? A systematic review published in the Lancet in December 2017 suggests that it is. The review found that using atraumatic ...
    • Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: A clinical practice guideline 

      Helsingen, Lise M; Vandvik, Per Olav; Jodal, Henriette C; Agoritsas, Thomas; Lytvyn, Lyubov; Anderson, Joseph C; Auer, Reto; Murphy, Silje Bjerkelund; Almadi, Majid Abdulrahman; Corley, Douglas A; Quinlan, Casey; Fuchs, Jonathan M; McKinnon, Annette; Qaseem, Amir; Heen, Anja Fog; Siemieniuk, Reed A.C.; Kalager, Mette; Usher-Smith, Juliet A.; Lansdorp-Vogelaar, Iris; Bretthauer, Michael; Guyatt, Gordon (Journal article, 2019)
      CLINICAL QUESTION: Recent 15-year updates of sigmoidoscopy screening trials provide new evidence on the effectiveness of colorectal cancer screening. Prompted by the new evidence, we asked: "Does colorectal cancer screening ...
    • Corticosteroid therapy for sepsis: A clinical practice guideline 

      Lamontagne, François; Rochwerg, Bram; Lytvyn, Lyubov; Guyatt, Gordon H.; Møller, Morten Hylander; Annane, Djillali; Kho, Michelle E.; Adhikari, Neill K.J.; MacHado, Flavia; Vandvik, Per Olav; Dodek, Peter; Leboeuf, Rebecca; Briel, Matthias; Hashmi, Madiha; Camsooksai, Julie; Shankar-Hari, Manu; Baraki, Mahder Kinfe; Fugate, Karie; Chua, Shunjie; Marti, Christophe; Cohen, DIan; Botton, Edouard; Agoritsas, Thomas; Siemieniuk, Reed Alexander C. (Peer reviewed; Journal article, 2019)
      Do corticosteroids reduce death or improve recovery in people with sepsis or septic shock? Our panel make a weak recommendation to give corticosteroids to people with all types and severity of sepsis, based on new evidence. ...
    • Dipeptidyl peptidase-4 inhibitors and risk of heart failure in type 2 diabetes: Systematic review and meta-analysis of randomised and observational studies 

      Li, Ling; Li, Sheyu; Deng, Ke; Liu, Jiali; Vandvik, Per Olav; Zhao, Pujing; Zhang, Longhao; Shen, Jiantong; Bala, Malgorzata M.; Sohani, Zahra N.; Wong, Evelyn; Busse, Jason Walter; Ebrahim, Shanil; Malaga, German; Rios, Lorena P.; Wang, Yingqiang; Chen, Qunfei; Guyatt, Gordon Henry; Sun, Xin (Journal article; Peer reviewed, 2016)
      Objectives To examine the association between dipeptidyl peptidase-4 (DPP-4) inhibitors and the risk of heart failure or hospital admission for heart failure in patients with type 2 diabetes. Design Systematic review ...
    • Minimal important differences for improvement in shoulder condition patient-reported outcomes: A systematic review to inform a BMJ Rapid Recommendation 

      Hao, Quikui; Devji, Tahira; Zeraatkar, Dena; Wang, Yuting; Qasim, Anila; Siemieniuk, Reed A.C.; Vandvik, Per Olav; Lähdeoja, Tuomas; Carrasco-Labra, Alonso; Agoritsas, Thomas; Guyatt, Gordon (Peer reviewed; Journal article, 2019)
      OBJECTIVES: To identify credible anchor-based minimal important differences (MIDs) for patient-reported outcome measures (PROMs) relevant to a BMJ Rapid Recommendations addressing subacromial decompression surgery for ...
    • Patent foramen ovale closure, antiplatelet therapy or anticoagulation in patients with patent foramen ovale and cryptogenic stroke: a systematic review and network meta-analysis incorporating complementary external evidence 

      Mir, Hassan; Siemieniuk, Reed Alexander C.; Ge, Long Cruz; Foroutan, Farid; Fralick, Michael; Syed, Talha; Lopes, Luciane Cruz; Kuijpers, Ton; Mas, Jean-Louis; Vandvik, Per Olav; Agoritsas, Thomas; Guyatt, Gordon H (Journal article; Peer reviewed, 2018)
      OBJECTIVE: To examine the relative impact of three management options in patients aged <60 years with cryptogenic stroke and a patent foramen ovale (PFO): PFO closure plus antiplatelet therapy, antiplatelet therapy alone ...
    • Prostate cancer screening with prostate-specific antigen (PSA) test: A clinical practice guideline 

      Tikkinen, Kari A.O.; Dahm, Philipp; Lytvyn, Lyubov; Heen, Anja Fog; Vernooij, Robin W.M.; Siemieniuk, Reed A.C.; Wheeler, Russell; Vaughan, Bill; Fobuzi, Awah Cletus; Blanker, Marco H.; Junod, Noelle; Sommer, Johanna; Stirnemann, Jérôme; Yoshimura, Manabu; Auer, Reto; MacDonald, Helen; Guyatt, Gordon; Vandvik, Per Olav; Agoritsas, Thomas (Peer reviewed; Journal article, 2019)
      What is the role of prostate-specific antigen (PSA) screening in prostate cancer? An expert panel produced these recommendations based on a linked systematic review.1 The review was triggered by a large scale, cluster ...