Blar i SIHF Open Archive på tidsskrift "New England Journal of Medicine"

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    • A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease 

      Schuppan, Detlef; Maki, Markku; Lundin, Knut Erik Aslaksen; Isola, Jorma; Friesing-Sosnik, Tina; Taavela, Juha; Popp, Alina; Koskenpato, Jari; Langhorst, Jost; Hovde, Øistein; Lähdeaho, Marja-Leena; Fucso, Stefano; Schumann, Michael; Török, Helga-Paula; Kupcinskas, Jouzas; Zopf, Yurdagul; Lohse, Ansgar W.; Scheinin, Mika; Kull, Karin; Biedermann, Luc; Byrnes, Valerie; Stellmach, Andreas; Jahnsen, Jørgen; Zeitz, Jonas; Mohrbacher, Ralf; Greinwald, Roland (Peer reviewed; Journal article, 2021)
      Background: In celiac disease, small intestinal transglutaminase 2 causes deamidation of glutamine residues in gluten peptides, which enhances stimulation of T cells and leads to mucosal injury. Inhibition of transglutaminase ...