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dc.contributor.authorSolvik, Beate Stokke
dc.contributor.authorBakken, Kjersti Sletten
dc.contributor.authorMcCann, Adrian
dc.contributor.authorUeland, Per Magne
dc.contributor.authorHenjum, Sigrun
dc.contributor.authorStrand, Tor Arne
dc.date.accessioned2024-11-22T12:45:26Z
dc.date.available2024-11-22T12:45:26Z
dc.date.created2024-10-01T10:16:34Z
dc.date.issued2024
dc.identifier.citationSolvik BS, Bakken KS, McCann A, Ueland PM, Henjum S, Strand TA. Breastfeeding and biomarkers of folate and cobalamin status in Norwegian infants: a cross-sectional study. J Nutr Sci. 2024 Sep 19;13:e40en_US
dc.identifier.issn2048-6790
dc.identifier.urihttps://hdl.handle.net/11250/3166182
dc.description.abstractFolate and vitamin B12 (cobalamin) are essential for growth and development. This cross-sectional study aims to describe folate and vitamin B12 status according to infant age and breastfeeding practices in Norwegian infants. Infants aged 0–12 months (n = 125) were recruited through public health clinics.We registered breastfeeding status and measured serum concentrations of folate, cobalamin, total homocysteine (tHcy), and methylmalonic acid (MMA). The associations between infant age, breastfeeding, and biomarker concentrations were estimated in regression models. The mean (SD) age was 24 (16) weeks, and 42% were exclusively breastfed, 38% were partially breastfed, and 21% were weaned. Overall, median (IQR) folate, cobalamin, tHcy, andMMAconcentrations were 47 (35–66) nmol/L, 250 (178–368) pmol/L, 6.99 (5.69–9.27) μmol/L, and 0.35 (0.24–0.83) μmol/L, respectively. None of the infants were folate deficient, 15% were vitamin B12 deficient (6.5 μmol/L) andMMA (>0.26 μmol/L) were found in 62% and 69% of the infants, respectively. Compared to weaned, exclusively or partially breastfed infants were younger and had 46% higher tHcy concentrations (Pen_US
dc.description.abstractBreastfeeding and biomarkers of folate and cobalamin status in Norwegian infants: a cross-sectional studyen_US
dc.description.sponsorshipThis study was supported by Innlandet Hospital Trust Research Fund (grant number 150407 and 150392), Regional Research Fund Innlandet (grant number 286442).en_US
dc.language.isoengen_US
dc.publisherCambridge University Press on behalf of The Nutrition Societyen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.subjectBreastfeedingen_US
dc.subjectFolateen_US
dc.subjectHomocysteineen_US
dc.subjectMethylmalonic aciden_US
dc.subjectVitamin B12en_US
dc.titleBreastfeeding and biomarkers of folate and cobalamin status in Norwegian infants: a cross-sectional studyen_US
dc.title.alternativeBreastfeeding and biomarkers of folate and cobalamin status in Norwegian infants: a cross-sectional studyen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.rights.holder© The Author(s) 2024.en_US
dc.source.pagenumber10en_US
dc.source.volume13en_US
dc.source.journalJournal of Nutritional Science (JNS)en_US
dc.identifier.doi10.1017/jns.2024.54
dc.identifier.cristin2307676
dc.relation.projectSykehuset Innlandet HF: 150407en_US
dc.relation.projectRegionale forskningsfond Innlandet: 286442en_US
dc.relation.projectRegionale forskningsfond Innlandet: 286442)en_US
dc.relation.projectSykehuset Innlandet HF: 150392en_US
dc.source.articlenumbere40en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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