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dc.contributor.authorHelvik, Anne-Sofie
dc.contributor.authorBarca, Maria Lage
dc.contributor.authorBergh, Sverre
dc.contributor.authorSaltyte Benth, Jurate
dc.contributor.authorKirkevold, Øyvind
dc.contributor.authorBorza, Tom
dc.identifier.citationBMC Geriatrics. 2019, 19 (1), .en_US
dc.description.abstractAbstract Background: Depressive symptoms in old age are common, but the prevalence, persistence, and incidence of depressive symptoms in older adults with and without dementia receiving in-home care is less well studied, and descriptions of the relationship between severity of cognitive decline and depressive symptoms over time is, to our knowledge, lacking. The aim of the present study was to describe the prevalence, incidence and persistence of depressive symptoms over a 36-month follow-up period among older adults receiving in-home care at baseline, and to explore the association between cognitive function and the course of depressive symptoms over time. Methods: In all, 1001 older people (≥ 70 years) receiving in-home care were included in a longitudinal study with three assessments over 36 months. Depressive symptoms were assessed using the Cornell Scale for Depression in Dementia. Clinical Dementia Rating Scale, diagnosis of dementia and mild cognitive impairment, general medical health, personal and instrumental activities of daily living, neuropsychiatric symptoms and the use of psychotropic medication were evaluated during the three assessments. Baseline demographic characteristics and information on nursing home residency at follow-up were recorded. Linear mixed models were estimated. Results: The baseline prevalence and cumulative incidence of single depressive symptoms were higher in those with dementia at baseline than in those without dementia. The persistence of depressive symptoms did not differ between those with or without dementia at baseline. The severity of cognitive impairment and mean depressive symptom score assessed simultaneously were positively associated, but the strength of the association changed over time and was not significant at the last assessment. Furthermore, being younger, female, in very poor physical health, with neuropsychiatric symptoms and not becoming a nursing home resident were associated with more depressive symptoms when assessed simultaneously. Conclusion: The baseline prevalence and cumulative incidence of depressive symptoms in those with and without dementia at baseline, as well as the relationship we found between the degree of cognitive decline and depressive symptoms over time show that depression and dementia are interconnected. Nurses and clinicians should pay attention to cognitive status when observing or evaluating depression among older adults receiving in-home care. Keywords: Cognitive decline, CSDD, Depressive symptoms, Depression, Domiciliary care, Elderly, Home care, Neuropsychiatric inventory, Symptom load, Physical diseaseen_US
dc.description.sponsorshipData collection was financed by the Norwegian Directorate of Health and Innlandet Hospital trust. The funders did not take part in the design of the study; collection, analysis, interpretation of data, or in writing the manuscript.en_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.subjectCognitive decline;en_US
dc.subjectDepressive symptoms;en_US
dc.subjectDomiciliary care;en_US
dc.subjectHome care;en_US
dc.subjectNeuropsychiatric inventory;en_US
dc.subjectPhysical disease;en_US
dc.subjectSymptom loaden_US
dc.titleThe course of depressive symptoms with decline in cognitive function - a longitudinal study of older adults receiving in-home care at baselineen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.rights.holder© The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.en_US
dc.source.journalBMC Geriatricsen_US
cristin.unitnameAvd Alderspsykiatri

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