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dc.contributor.authorHestad, Knut
dc.contributor.authorAukrust, P.
dc.contributor.authorTønseth, S
dc.contributor.authorReitan, Solveig Klæbo
dc.date.accessioned2018-06-01T08:14:18Z
dc.date.available2018-06-01T08:14:18Z
dc.date.created2010-01-02T20:51:13Z
dc.date.issued2009
dc.identifier.citationCurrent Psychiatry Reviews. 2009, 5 287-297.nb_NO
dc.identifier.issn1573-4005
dc.identifier.urihttp://hdl.handle.net/11250/2500007
dc.description.abstractEpidemiological findings indicate a connection between depressive symptoms and changes in status of the immune system in depressed patients. This raises the possibility of causative connections. Theories on mechanisms for interactions between immune and affective systems – directly and via endocrine system – are evolving. Such hypothesized causative connections are supported by several findings. First, in depressed patients changes in the status of the immune system in vivo and ex vivo are seen. Also, depressive symptoms are seen in patients with altered immune status (physiologically, pathologically or chemically induced). Knowledge in this field may have implications regarding psychiatric follow up of physically ill people suffering from diseases caused by an altered immune system (long lasting infections, autoimmune diseases, hypersensitivity disorders) as well as disorders for which treatment and prognoses depends on the immune system (infections, cancer). Similarly, medical treatment of depressed patients may be adjusted by more specific knowledge about the interaction between neuroimmunology and depression. Important findings and the present knowledge and theories are reviewed.nb_NO
dc.language.isoengnb_NO
dc.subjectDepressionnb_NO
dc.subjectimmunologynb_NO
dc.subjectendocrinologynb_NO
dc.subjectneurologynb_NO
dc.subjectinflammationnb_NO
dc.subjectbrainnb_NO
dc.subjectpsychiatrynb_NO
dc.titleDepression has a strong relationship to alterations in the immune, endocrine ad neural systemnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionacceptedVersionnb_NO
dc.rights.holder© 2009 Bentham Science Publishers Ltd.nb_NO
dc.source.pagenumber287-297nb_NO
dc.source.volume5nb_NO
dc.source.journalCurrent Psychiatry Reviewsnb_NO
dc.identifier.cristin500673
cristin.unitcode1991,0,0,0
cristin.unitnameSykehuset Innlandet HF
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1


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