Blar i SIHF Open Archive på forfatter "Hestad, Knut"
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APOE – a genetic marker of comorbidity in subjects with morbid obesity
Farup, Per Grønaas; Rootwelt, Helge; Hestad, Knut (Peer reviewed; Journal article, 2020)Background: In population-based studies, the genetic variability of the APOE E alleles have been associated with health outcomes. Health problems are common in subjects with obesity. This study explored associations between ... -
The Applicability of the Patient-Specific Functional Scale (PSFS) in Rehabilitation for Patients with Acquired Brain Injury (ABI) – A Cohort Study
Evensen, Janne; Søberg, Helene Lundgaard; Sveen, Unni; Hestad, Knut; Bronken, Berit Arnesveen (Peer reviewed; Journal article, 2020)Aim: The primary aim of this study was to investigate the applicability of the Patient-Specific Functional Scale (PSFS) in patients with acquired brain injury (ABI) admitted to a specialized rehabilitation unit in a regional ... -
Blood pressure in dementia, mild cognitive impairment, and subjective cognitive decline related to time of death
Hestad, Knut; Engedal, Knut; Selbæk, Geir; Strand, Bjørn Heine (Peer reviewed; Journal article, 2021)Objective: It is unknown whether systolic blood pressure (SBP) drop is part of the normal aging process or due to the onset of dementia for some people. SBP drop is referring to the decrease in blood pressure often seen ... -
Cognitive Functions and Depression in Patients with Irritable Bowel Syndrome
Farup, Per Grønaas; Hestad, Knut (Journal article; Peer reviewed, 2015)Background. Irritable bowel syndrome (IBS) is associated with depression and depression with impaired cognitive functions. The primary aim was to study associations between depression and cognitive functions in patients ... -
Cognitive impairment in Zambians with HIV infection and pulmonary tuberculosis
Hestad, Knut; Chinyama, Jonathan; Anitha, Menon J; Ngoma, Mary S.; McCutchan, J. Allen; Franklin, Donald R.; Heaton, Robert K. (Peer reviewed; Journal article, 2019)BACKGROUND: HIV infection may result in neurocognitive deficits, but the effects of pulmonary tuberculosis (TB+), a common comorbid condition in HIV infection, on cognition in HIV infections are unknown. Accordingly, we ... -
Depression has a strong relationship to alterations in the immune, endocrine ad neural system
Hestad, Knut; Aukrust, P.; Tønseth, S; Reitan, Solveig Klæbo (Journal article; Peer reviewed, 2009)Epidemiological findings indicate a connection between depressive symptoms and changes in status of the immune system in depressed patients. This raises the possibility of causative connections. Theories on mechanisms for ... -
Effect of Age and Level of Education on Neurocognitive Impairment in HIV Positive Zambian Adults
Kabuba, Norma Namasiku Zewelanji; Menon, Anitha; Franklin, Donald R.; Lydersen, Stian; Heaton, Robert K.; Hestad, Knut (Peer reviewed; Journal article, 2018)Objective: Older age and lower education levels are known to be associated with worse neurocognitive (NC) performance in healthy adults, and individuals with HIV infection may experience accelerated brain/cognition aging. ... -
The effect of blood pressure on cognitive performance. An 8-year follow-up of the Tromsø Study, comprising people aged 45–74 Years
Hestad, Knut; Engedal, Knut; Schirmer, Henrik; Strand, Bjørn Heine (Peer reviewed; Journal article, 2020)Background: The relationship between blood pressure (BP) and cognition is complex were age appears to be an intervening variable. High and low BP have been associated with cognitive deficits as part of the aging process, ... -
Functional Bowel Disorders Are Associated with a Central Immune Activation
Farup, Per Grønaas; Ueland, Thor; Rudi, Knut; Lydersen, Stian; Hestad, Knut (Journal article; Peer reviewed, 2017)Background. Subjects with depression and unexplained neurological symptoms have a high prevalence of gastrointestinal comorbidity probably related to the brain-gut communication. This study explored associations between ... -
High frequency and intensity of drinking may attenuate increased inflammatory cytokine levels of major depression in alcohol-use disorders
Neupane, Sudan Prasad; Lien, Lars; Martinez, Priscilla; Aukrust, Pål; Ueland, Thor; Mollnes, Tom Eirik; Hestad, Knut; Bramness, Jørgen Gustav (Peer reviewed; Journal article, 2014)As major depression (MD) is often comorbid with alcohol-use disorders (AUD) and alcohol itself modulates the immune system, we examined serum levels of interleukin (IL)-6, IL-10, tumor necrosis factor (TNF), and interferon ... -
Neurocognitive Outcome and Compensating Possibilities in Children and Adolescents Treated for Acute Lymphoblastic Leukemia With Chemotherapy Only
Lofstad, Grete Elisabeth; Reinfjell, Trude; Weider, Siri; Diseth, Trond H; Hestad, Knut (Journal article; Peer reviewed, 2019)Aim: To examine the neurocognitive outcomes in children and adolescents with acute lymphoblastic leukemia (ALL) in remission who were treated with systemic chemotherapy only (CTO). Methods: Neurocognitive performances in ... -
Predicting acute side effects of stimulant medication in pediatric attention deficit/hyperactivity disorder: data from quantitative electroencephalography, event-related potentials, and a continuous-performance test
Øgrim, Kjell Geir; Hestad, Knut; Brunner, Jan; Kropotov, Yury (Journal article; Peer reviewed, 2013)Abstract BACKGROUND: The aim of this study was to search for predictors of acute side effects of stimulant medication in pediatric attention deficit/hyperactivity disorder (ADHD), emphasizing variables from quantitative ... -
Predicting the clinical outcome of stimulant medication in pediatric attention-deficit/hyperactivity disorder: data from quantitative electroencephalography, event-related potentials, and a go/no-go test
Øgrim, Kjell Geir; Kropotov, Yury; Brunner, Jan; Candrian, Gian; Sandvik, Leiv; Hestad, Knut (Journal article; Peer reviewed, 2014)Abstract BACKGROUND: We searched for predictors of the clinical outcome of stimulant medication in pediatric attention-deficit/hyperactivity disorder (ADHD), emphasizing variables from quantitative electroencephalography, ... -
The Relationships among Tryptophan, Kynurenine, Indoleamine 2,3-Dioxygenase, Depression, and Neuropsychological Performance
Hestad, Knut; Engedal, Knut; Whist, Jon Elling; Farup, Per Grønaas (Journal article; Peer reviewed, 2017)It has been suggested that the metabolic enzyme indoleamine 2,3-dioxygenase (IDO) is a biological mediator of inflammation related to the psychopathology of depression, with a Kynurenine (KYN) increase in the Tryptophan ... -
Visual-Constructional Ability in Individuals with Severe Obesity: Rey Complex Figure Test Accuracy and the Q-Score
Sargenius, Hanna; Bylsma, Frederick; Lydersen, Stian; Hestad, Knut (Journal article; Peer reviewed, 2017)The aims of this study were to investigate visual-construction and organizational strategy among individuals with severe obesity, as measured by the Rey Complex Figure Test (RCFT), and to examine the validity of the Q-score ...