• Frailty identified by geriatric assessment is associated with poor functioning, high symptom burden and increased risk of physical decline in older cancer patients: Prospective observational study 

      Kirkhus, Lene; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Hjermstad, Marianne Jensen; Rostoft, Siri; Harneshaug, Magnus; Selbæk, Geir; Wyller, Torgeir Bruun; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2019)
      Background: Maintaining quality of life including physical functioning is highly prioritized among older cancer patients. Geriatric assessment is a recommended approach to identify patients with increased vulnerability ...
    • Geriatric assessment is superior to oncologists’ clinical judgement in identifying frailty 

      Kirkhus, Lene; Saltyte Benth, Jurate; Kristjansson, Siri Rostoft; Grønberg, Bjørn Henning; Hjermstad, Marianne Jensen; Selbæk, Geir; Wyller, Torgeir Bruun; Harneshaug, Magnus; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2017)
      Background: Frailty is a syndrome associated with increased vulnerability and an important predictor of outcomes in older cancer patients. Systematic assessments to identify frailty are seldom applied, and oncologists’ ...
    • Health-related quality of life in older depressed psychogeriatric patients: one year follow-up 

      Helvik, Anne-Sofie; Corazzini, Kirsten; Selbæk, Geir; Björklöf, Guro Hanevold; Laks, Jerson; Saltyte Benth, Jurate; Østbye, Truls; Engedal, Knut (Peer reviewed; Journal article, 2016)
      Background: Knowledge about long-term change in health related quality of life (HQoL) among older adults after hospitalization for treatment of depression has clinical relevance. The aim was firstly to describe the change ...
    • Informal and formal care among persons with dementia immediately before nursing home admission 

      Ydstebø, Arnt Egil; Saltyte Benth, Jurate; Bergh, Sverre; Selbæk, Geir; Vossius, Corinna Elisabeth (Peer reviewed; Journal article, 2020)
      Background: Dementia is a care intensive disease, especially in the later stages, implying in many cases a substantial carer burden. This study assesses the use of formal and informal care resources among persons with ...
    • Meta-analysis of Alzheimer’s disease on 9,751 samples from Norway and IGAP study identifies four risk loci 

      Witoelar, Aree; Rongve, Arvid; Almdahl, Ina Selseth; Ulstein, Ingun; Engvig, Andreas; White, Linda Rosemary; Selbæk, Geir; Stordal, Eystein; Andersen, Fredrik; Brækhus, Anne; Saltvedt, Ingvild; Engedal, Knut; Hughes, Timothy; Bergh, Sverre; Bråthen, Geir; Bogdanovic, Nenad; Bettella, Francesco; Wang, Yunpeng; Athanasiu, Lavinia; Bahrami, Shahram; Le Hellard, Stephanie; Giddaluru, Sudheer; Dale, Anders M; Sando, Sigrid Botne; Steinberg, Stacy; Stefansson, Hreinn; Snaedal, Jon; Desikan, Rahul S; Stefansson, Kari; Aarsland, Dag; Djurovic, Srdjan; Fladby, Tormod; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2018)
      A large fraction of genetic risk factors for Alzheimer's Disease (AD) is still not identified, limiting the understanding of AD pathology and study of therapeutic targets. We conducted a genome-wide association study (GWAS) ...
    • Midlife Physical Activity, Psychological Distress, and Dementia Risk: The HUNT Study 

      Zotcheva, Ekaterina; Bergh, Sverre; Selbæk, Geir; Krokstad, Steinar; Håberg, Asta; Strand, Bjørn Heine; Ernstsen, Linda (Peer reviewed; Journal article, 2018)
      BACKGROUND: Physical activity (PA) is associated with a decreased dementia risk, whereas psychological distress (distress) is linked to an increased dementia risk. OBJECTIVE: We investigated independent and joint ...
    • Mobility and cognition at admission to the nursing home – a cross-sectional study 

      Sverdrup, Karen; Bergh, Sverre; Selbæk, Geir; Røen, Irene Mari; Kirkevold, Øyvind; Tangen, Gro Gujord (Peer reviewed; Journal article, 2018)
      Background Earlier studies show that the main reasons for admission to long-term nursing home care are cognitive impairment and functional impairments of activities of daily life. However, descriptive evidence of mobility ...
    • Modifiable factors affecting older patients' quality of life and physical function during cancer treatment 

      Kirkhus, Lene; Harneshaug, Magnus; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Rostoft, Siri; Bergh, Sverre; Hjermstad, Marianne Jensen; Selbæk, Geir; Wyller, Torgeir Bruun; Kirkevold, Øyvind; Borza, Tom; Saltvedt, Ingvild; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2019)
      BACKGROUND: Maintaining physical function and quality of life (QoL) are prioritized outcomes among older adults. We aimed to identify potentially modifiable factors affecting older patients' physical function and QoL ...
    • Mortality in nursing home residents: A longitudinal study over three years 

      Vossius, Corinna Elisabeth; Selbæk, Geir; Saltyte Benth, Jurate; Bergh, Sverre (Journal article; Peer reviewed, 2018)
      OBJECTIVE: Nursing home (NH) stay is the highest level of formal care. With the expected demographic changes ahead, the need for NH placement will put an increasing socioeconomic strain on the society. Survival in NHs ...
    • Mortality in older adults with frequent alcohol consumption and use of drugs with addiction potential – The Nord Trøndelag Health Study 2006-2008 (HUNT3), Norway, a population-based study 

      Tevik, Kjerstin Elisabeth; Selbæk, Geir; Engedal, Knut; Seim, Arnfinn; Krokstad, Steinar; Helvik, Anne-Sofie (Journal article; Peer reviewed, 2019)
      BACKGROUND: The aim of this study was to investigate whether frequent drinking, use of drugs with addiction potential and the possible combination of frequent drinking and use of prescribed drugs with addiction potential ...
    • MRI-assessed atrophy subtypes in Alzheimer’s disease and the cognitive reserve hypothesis 

      Persson, Karin; Eldholm, Rannveig Sakshaug; Barca, Maria Lage; Cavallin, Lena; Ferreira, Daniel; Knapskog, Anne Brita; Selbæk, Geir; Brækhus, Anne; Saltvedt, Ingvild; Westman, Eric; Engedal, Knut (Journal article; Peer reviewed, 2017)
      Background/Aims MRI assessment of the brain has demonstrated four different patterns of atrophy in patients with Alzheimer’s disease dementia (AD): typical AD, limbic-predominant AD, hippocampal-sparing AD, and a subtype ...
    • MRI-based classification models in prediction of mild cognitive impairment and dementia in late-life depression 

      Lebedeva, Aleksandra K.; Westman, Eric; Borza, Tom; Beyer, Mona K.; Engedal, Knut; Aarsland, Dag; Selbæk, Geir; Håberg, Asta (Journal article; Peer reviewed, 2017)
      Objective: Late-life depression (LLD) is associated with development of different types of dementia. Identification of LLD patients, who will develop cognitive decline, i.e., the early stage of dementia would help to ...
    • Multi-psychotropic drug prescription and the association to neuropsychiatric symptoms in three Norwegian nursing home cohorts between 2004 and 2011 

      Gulla, Christine; Selbæk, Geir; Flo, Elisabeth; Kjome, Reidun Lisbet Skeide; Kirkevold, Øyvind; Husebø, Bettina (Peer reviewed; Journal article, 2016)
      Abstract BACKGROUND: Neuropsychiatric symptoms, such as affective symptoms, psychosis, agitation, and apathy are common among nursing home patients with and without dementia. Treatment with one or more psychotropic drug ...
    • Optimizing access to and use of formal dementia care: Qualitative findings from the European Actifcare study 

      Kerpershoek, Liselot; Wolfs, Claire; Verhey, Frans; Jelley, Hannah; Woods, Bob; Bieber, Anja; Bartoszek, Gabriele; Stephan, Astrid; Selbæk, Geir; Eriksen, Siren; Sjölund, Britt-Marie; Hopper, Louise; Irving, Kate; Goncalves-Pereira, Manuel; Portolani, Daniel; Zanetti, Orazio; Vugt, Marjolein (Journal article; Peer reviewed, 2019)
      This paper reports on qualitative data from the Actifcare study investigating experiences, attitudes, barriers and facilitators concerning access to and use of formal care. A total of 85 semi-structured in-depth interviews ...
    • Persistent use of psychotropic drugs in nursing home residents in Norway 

      Helvik, Anne-Sofie; Saltyte Benth, Jurate; Wu, Bei; Engedal, Knut; Selbæk, Geir (Journal article; Peer reviewed, 2017)
      Background The prevalence of psychotropic drug (PTD) use in NH residents is high, but few have explored prevalence and persistency in PTD in NH residents and factors associated with persistency. This at the same time as ...
    • Physical diagnoses in nursing home residents - is dementia or severity of dementia of importance? 

      Jørgensen, Live Bredholt; Thorleifsson, Berit Marie; Selbæk, Geir; Saltyte Benth, Jurate; Helvik, Anne-Sofie (Journal article; Peer reviewed, 2018)
      BACKGROUND: Dementia and physical morbidity are primary reasons for nursing home admission globally. However, data on physical morbidity in nursing home residents with and without dementia are scarce. The first aim of the ...
    • Predictors for Nursing Home Admission and Death among Community-Dwelling People 70 Years and Older Who Receive Domiciliary Care 

      Wergeland, Jon Normann; Selbæk, Geir; Bergh, Sverre; Söderhamn, Ulrika; Kirkevold, Øyvind (Journal article; Peer reviewed, 2015)
      Aim: The aim of this study was to analyze which variables predicted nursing home admission (NHA) and death. Methods: 1,001 recipients of domiciliary care were assessed three times in a 3-year period. Through bivariate and ...
    • Quality of Life in People with Young-Onset Dementia: A Nordic Two-Year Observational Multicenter Study 

      Hvidsten, Lara H. Thomasgaard; Engedal, Knut; Selbæk, Geir; Wyller, Torgeir Bruun; Saltyte Benth, Jurate; Kersten, Hege (Peer reviewed; Journal article, 2019)
      Background:Cross-sectional studies of quality of life (QOL) of people with young-onset dementia show diverging results. Objective:To identify factors associated with QOL in people with young-onset Alzheimer’s (AD) and ...
    • Quality of life of family carers of persons with young-onset compared to late-onset dementia 

      Hvidsten, Lara H. Thomasgaard; Engedal, Knut; Selbæk, Geir; Wyller, Torgeir Bruun; Saltyte Benth, Jurate; Bruvik, Frøydis Kristine; Kersten, Hege (Journal article; Peer reviewed, 2019)
      Abstract OBJECTIVES: To compare quality of life (QOL) of family carers of persons with young- (YOD) to late-onset dementia (LOD). METHODS: This was a cross-sectional comparison of 88 carers of persons with YOD and ...
    • Relationship quality and sense of coherence in dementia: Results of a European cohort study 

      Marques, Maria J.; Woods, Bob; Hopper, Louise; Jelley, Hannah; Irving, Kate; Kerpershoek, Liselot; Meyer, Gabriele; Bieber, Anja; Stephan, Astrid; Sköldunger, Anders; Sjölund, Britt-Marie; Selbæk, Geir; Røsvik, Janne-Kathrin; Zanetti, Orazio; Portolani, Elisa; de Vugt, Marjolein; Verhey, Frans; Gonçalves‐Pereira, Manuel (Journal article; Peer reviewed, 2019)
      Objective Quality of life of people with dementia and their family carers is strongly influenced by interpersonal issues and personal resources. In this context, relationship quality (RQ) and sense of coherence (SOC) ...