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Gadolinium in Medical Imaging - Usefulness, Toxic Reactions and Possible Countermeasures - A Review
(Peer reviewed; Journal article, 2022)Gadolinium (Gd) is one of the rare-earth elements. The properties of its trivalent cation (Gd3+) make it suitable to serve as the central ion in chelates administered intravenously to patients as a contrast agent in magnetic ... -
Gender differences in association between uric acid and all-cause mortality in patients with chronic heart failure
(Journal article; Peer reviewed, 2019)BACKGROUND: Elevated serum uric acid (SUA) is associated with poor prognosis in patients with cardiovascular disease, yet it is still not decided whether the role of SUA is causal or only reflects an underlying disease. ... -
Genetic and clinical variations in a Norwegian sample diagnosed with Rett syndrome
(Peer reviewed; Journal article, 2020)Background and purpose: Rett syndrome (RTT) is a neurodevelopmental disorder mainly caused by mutations in MECP2. The diagnostic criteria of RTT are clinical; mutations in MECP2 are neither diagnostic nor necessary, and a ... -
Genetic variation in catechol-O-methyltransferase modifies effects of clonidine treatment in chronic fatigue syndrome
(Peer reviewed; Journal article, 2016)Abstract Clonidine, an α2-adrenergic receptor agonist, decreases circulating norepinephrine and epinephrine, attenuating sympathetic activity. Although catechol-O-methyltransferase (COMT) metabolizes catecholamines, ... -
Geriatric assessment is superior to oncologists’ clinical judgement in identifying frailty
(Journal article; Peer reviewed, 2017)Background: Frailty is a syndrome associated with increased vulnerability and an important predictor of outcomes in older cancer patients. Systematic assessments to identify frailty are seldom applied, and oncologists’ ... -
Gestational Age, Birth Weight, and Neurocognitive Development in Adolescents in Tanzania
(Peer reviewed; Journal article, 2021)Objectives: To investigate the association between gestational age, birthweight, and birthweight adjusted for gestational age, with domains of neurocognitive development and behavioral problems in adolescents in Tanzania. ... -
Global burden of acute lower respiratory infection associated with human metapneumovirus in children under 5 years in 2018: a systematic review and modelling study
(Peer reviewed; Journal article, 2020)Background: Human metapneumovirus is a common virus associated with acute lower respiratory infections (ALRIs) in children. No global burden estimates are available for ALRIs associated with human metapneumovirus in children, ... -
Gut Microbiota as a Mediator of Essential and Toxic Effects of Zinc in the Intestines and Other Tissues
(Peer reviewed; Journal article, 2021)The objective of the present study was to review the existing data on the association between Zn status and characteristics of gut microbiota in various organisms and the potential role of Zn-induced microbiota in modulating ... -
Gut microbiota composition during a 12-week intervention with delayed-release dimethyl fumarate in multiple sclerosis – a pilot trial
(Peer reviewed; Journal article, 2019)Introduction: Patients with multiple sclerosis may have a distinct gut microbiota profile. Delayed-release dimethyl fumarate is an orally administered drug for relapsing-remitting multiple sclerosis, which has been associated ... -
Haemodynamic effects of methoxyflurane versus fentanyl and placebo in hypovolaemia: a randomised, double-blind crossover study in healthy volunteers
(Peer reviewed; Journal article, 2023)Background: Methoxyflurane is approved for relief of moderate to severe pain in conscious adult trauma patients: it may be self-administrated and is well suited for use in austere environments. Trauma patients may sustain ... -
Hair Lead, Aluminum, and Other Toxic Metals in Normal-Weight and Obese Patients with Coronary Heart Disease
(Peer reviewed; Journal article, 2021)Abstract The objective of the present study was to evaluate hair toxic metal levels in patients with obesity and/or coronary heart disease (CHD). Following a 2 × 2 factorial design, subjects without CHD were grouped into ... -
Health-related behaviors in adolescents mediate the association between subjective social status and body mass index
(Peer reviewed; Journal article, 2020)The aim of this study was to explore the association between adolescent subjective social status (SSS) and body mass index (BMI) at two different time points and to determine whether this association was mediated by ... -
Health-related quality of life in older depressed psychogeriatric patients: one year follow-up
(Peer reviewed; Journal article, 2016)Background: Knowledge about long-term change in health related quality of life (HQoL) among older adults after hospitalization for treatment of depression has clinical relevance. The aim was firstly to describe the change ... -
Helpful Ingredients in the Treatment of Long-Term Substance Use Disorders: A Collaborative Narrative Study
(Peer reviewed; Journal article, 2019)Relatively few individuals with a substance use disorder (SUD) seek or receive treatment, and knowledge about the effective ingredients in SUD treatment, from the perspective of those who receive it, is scarce. Our study ... -
Hepatitis C treatment uptake among people who inject drugs in Oslo, Norway: A registry-based study
(Peer reviewed; Journal article, 2023)Background Improving HCV treatment uptake among people who inject drugs (PWID) is crucial to achieving the WHO elimination targets. The aims were to evaluate HCV treatment uptake and HCV RNA prevalence in a large cohort ... -
High degree of uncertain reflective functioning in mothers with substance use disorder
(Peer reviewed; Journal article, 2019)AIMS: Having a substance use disorder (SUD) is associated with impaired reflective functioning (RF) or mentalizing, implying reduced capacity to reflect on internal mental states of the self and others. This has adverse ... -
High frequency and intensity of drinking may attenuate increased inflammatory cytokine levels of major depression in alcohol-use disorders
(Peer reviewed; Journal article, 2014)As major depression (MD) is often comorbid with alcohol-use disorders (AUD) and alcohol itself modulates the immune system, we examined serum levels of interleukin (IL)-6, IL-10, tumor necrosis factor (TNF), and interferon ... -
High levels of anomalous self-experience are associated with longer duration of untreated psychosis
(Peer reviewed; Journal article, 2017)Aim To investigate the relationship between anomalous self-experiences and duration of untreated psychosis in a sample of patients with first episode schizophrenia spectrum disorders. Methods Anomalous self-experiences ... -
HINT1 neuropathy in Norway: clinical, genetic and functional profiling
(Peer reviewed; Journal article, 2021)Background: Autosomal recessive axonal neuropathy with neuromyotonia has been linked to loss of functional HINT1. The disease is particularly prevalent in Central and South-East Europe, Turkey and Russia due to the high ...